Usefulness of prophylactic transcatheter arterial infusion of anticancer agents with lipiodol to prevent recurrence of hepatocellular carcinoma after hepatic resection

Shinji Togo; Kuniya Tanaka; Hidenobu Masui; Kenichi Matsuo; Daisuke Morioka; Haruki Kurosawa; Yasuhiko Miura; Itaru Endo; Hitoshi Sekido; Hiroshi Shimada

Usefulness of prophylactic transcatheter arterial infusion of anticancer agents with lipiodol to prevent recurrence of hepatocellular carcinoma after hepatic resection

Int Surg. 2005 Apr-Jun;90(2):103-8.

Authors

Shinji Togo¹, Kuniya Tanaka, Hidenobu Masui, Kenichi Matsuo, Daisuke Morioka, Haruki Kurosawa, Yasuhiko Miura, Itaru Endo, Hitoshi Sekido, Hiroshi Shimada

Affiliation

¹ Department of Surgery II, Yokohama City University School of Medicine, Yokohama, Japan. [email protected]

PMID: 16119716

Abstract

To improve the prognosis after hepatectomy for HCC, repeated postoperative transcatheter arterial infusions of anticancer drugs and lipiodol (TAI) were given. TAI may be effective as an adjuvant therapy for prevention of residual liver recurrence after hepatectomy, probably by suppression of the development of intrahepatic micrometastases rather than of multicentric carcinogenesis.

MeSH terms

Aged
Antineoplastic Agents / administration & dosage*
Carcinoma, Hepatocellular / surgery*
Chemoprevention
Contrast Media / administration & dosage
Female
Hepatectomy / adverse effects*
Humans
Infusions, Intra-Arterial
Iodized Oil / administration & dosage
Liver Neoplasms / surgery*
Male
Middle Aged
Neoplasm Recurrence, Local / etiology
Neoplasm Recurrence, Local / prevention & control*

Substances

Antineoplastic Agents
Contrast Media
Iodized Oil