Abstract
In this study we randomly compared the estradiol eluting stent (17-beta-E) with phosphorylcholine (PC)-coated stents in native coronary arteries. The incidence of angiographic restenosis was 23% in the 17-beta-E group and 31% in the PC group (p = 0.34). The major adverse cardiovascular event rates were also similar in the 2 groups (17% in the 17-beta-E group vs 22% in the PC group, p = 0.47). The mid-term clinical and angiographic outcomes did not indicate superiority of the 17-beta-E eluting stent over the control PC stent.
Publication types
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Clinical Trial
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Multicenter Study
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Randomized Controlled Trial
MeSH terms
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Angioplasty, Balloon, Coronary / instrumentation*
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Coated Materials, Biocompatible*
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Coronary Angiography
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Coronary Disease / diagnostic imaging
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Coronary Disease / therapy*
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Coronary Restenosis / diagnostic imaging
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Coronary Restenosis / epidemiology
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Coronary Restenosis / prevention & control
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Estradiol / therapeutic use*
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Female
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Follow-Up Studies
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Humans
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Incidence
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Italy / epidemiology
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Male
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Middle Aged
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Phosphorylcholine / therapeutic use*
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Retrospective Studies
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Stents*
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Treatment Outcome
Substances
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Coated Materials, Biocompatible
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Phosphorylcholine
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Estradiol