ProLysED: an integrated database and meta-server of bacterial protease systems

Appl Bioinformatics. 2005;4(2):147-50. doi: 10.2165/00822942-200504020-00009.

Abstract

Bacterial proteases are an important group of enzymes that have very diverse biochemical and cellular functions. Proteases from prokaryotic sources also have a wide range of uses, either in medicine as pathogenic factors or in industry and therapeutics. ProLysED (Prokaryotic Lysis Enzymes Database), our meta-server integrated database of bacterial proteases, is a useful, albeit very niche, resource. The features include protease classification browsing and searching, organism-specific protease browsing, molecular information and visualisation of protease structures from the Protein Data Bank (PDB) as well as predicted protease structures.

Availability: ProLysED is integrated into the ProLysES (Prokaryotic Lysis Enzymes Site) website at http://genome.ukm.my/prolyses/. Access to the ProLysED database is free for academic users upon registration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / classification
  • Computer Graphics
  • Database Management Systems*
  • Databases, Protein*
  • Information Storage and Retrieval / methods*
  • Internet*
  • Molecular Sequence Data
  • Peptide Hydrolases / chemistry*
  • Peptide Hydrolases / classification
  • Protein Conformation
  • Systems Integration
  • User-Computer Interface*

Substances

  • Bacterial Proteins
  • Peptide Hydrolases