Comparison of technetium-99m-MIBI and thallium-201-chloride uptake in primary thyroid lymphoma

J Nucl Med. 1992 Jul;33(7):1396-8.

Abstract

A case of primary thyroid lymphoma demonstrating uptake of 99mTc-hexakis-2-methoxy isobutyl isonitrile (MIBI) is presented. The 99mTc-MIBI image more clearly delineated the extent of tumor as demonstrated on CT compared to 201Tl-chloride and [99mTc]pertechnetate images. Following two courses of chemotherapy, repeat radionuclide studies and CT scan showed complete resolution of the thyroid tumor. Technetium-99m-MIBI may be useful in the assessment of disease activity and monitoring response to treatment in patients with lymphoma.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Female
  • Humans
  • Lymphoma, B-Cell / diagnostic imaging*
  • Lymphoma, B-Cell / metabolism
  • Lymphoma, Large B-Cell, Diffuse / diagnostic imaging*
  • Lymphoma, Large B-Cell, Diffuse / metabolism
  • Middle Aged
  • Nitriles / pharmacokinetics*
  • Organotechnetium Compounds / pharmacokinetics*
  • Radionuclide Imaging
  • Technetium Tc 99m Sestamibi
  • Thallium Radioisotopes / pharmacokinetics*
  • Thyroid Neoplasms / diagnostic imaging*
  • Thyroid Neoplasms / metabolism

Substances

  • Nitriles
  • Organotechnetium Compounds
  • Thallium Radioisotopes
  • Technetium Tc 99m Sestamibi