Abstract
Longitudinal F-actin cables are thought to be important for transporting materials for polarized cell growth in fission yeast. We show that most F-actin in the cables is oriented such that the barbed end faces the nearest cell tip during interphase; however, this directionality is reversed during mitosis. These orientations of F-actin ensure proper transport of materials to growing sites during these cell-cycle stages.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Actin Cytoskeleton / metabolism
-
Actin Cytoskeleton / ultrastructure
-
Actins / metabolism*
-
Actins / ultrastructure
-
Cell Cycle / physiology*
-
Cell Enlargement
-
Cell Polarity / physiology*
-
Microscopy, Electron, Transmission
-
Mitosis / physiology*
-
Myosins / metabolism
-
Protein Structure, Tertiary / physiology
-
Protein Transport / physiology
-
Schizosaccharomyces / metabolism
-
Schizosaccharomyces / physiology*
-
Schizosaccharomyces / ultrastructure