Estimation of partition coefficients by MEKC part 2: anthocyanins

J Sep Sci. 2005 Aug;28(12):1285-90. doi: 10.1002/jssc.200500072.

Abstract

The octanol-water partition coefficients of seven anthocyanins (in neutral form, pH = 7.0) were measured by means of MEKC. A new iterative method for the estimation of migration time of electroosmotic flow (EOF) and micelles in MEKC is presented. This calculation is based on Gauss-Newton linearization of the dependence between migration indices and migration times of a set of suitable standards and the application of an advanced statistical evaluation procedure. The values of partition coefficients obtained with the aid of an iterative process are compared with values obtained on use of EOF and micelle markers.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthocyanins / chemistry
  • Anthocyanins / isolation & purification*
  • Chromatography, Micellar Electrokinetic Capillary / methods*
  • Chromatography, Micellar Electrokinetic Capillary / statistics & numerical data
  • Hydrogen-Ion Concentration
  • Hydrophobic and Hydrophilic Interactions
  • Micelles
  • Models, Statistical
  • Octanols
  • Water

Substances

  • Anthocyanins
  • Micelles
  • Octanols
  • Water