Abstract
The immune reconstitution syndrome caused by bacillus Calmette-Guerin (BCG) was found in 4 HIV-infected children who were immunized with BCG at birth. The localized, suppurative, BCG-related complications developed within 10 weeks after initiation of antiretroviral therapy. The incidence rate was 2.7 cases per 100 persons (95% confidence interval, 0.7-6.7). Patients responded well to treatment with isoniazid and rifampicin.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-HIV Agents / therapeutic use*
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Antitubercular Agents / therapeutic use
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BCG Vaccine / adverse effects*
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Child
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Female
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HIV Infections / complications*
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HIV Infections / drug therapy*
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Humans
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Infant
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Isoniazid / therapeutic use
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Rifampin / therapeutic use
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Tuberculosis, Lymph Node / chemically induced*
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Tuberculosis, Lymph Node / complications
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Tuberculosis, Lymph Node / drug therapy
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Tuberculosis, Lymph Node / pathology
Substances
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Anti-HIV Agents
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Antitubercular Agents
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BCG Vaccine
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Isoniazid
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Rifampin