[Studies on chemical constituents in the seeds of Nigella glandulifera]

Zhongguo Zhong Yao Za Zhi. 2005 Jul;30(13):980-3.
[Article in Chinese]

Abstract

Objective: To investigate the chemical constituents in the seeds of Nigella glandulifera.

Method: The chemical constituents were isolated and repeatedly purified on silica gel column. They were identified and structurally elucidated by means of physio-chemical constants and spectral analysis.

Result: Nine compounds were identified as nigellamose (I), alpha-hederin (II), 3-O-[beta-D-xylopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinpyranosyl]-hederagenin (III), sucrose (IV), stearic acid (V), 1-O-hexadecanolenin (VI), beta-sitosterol (VII), daucosterol (VIII) and p-hydroxybenzoic acid (IX).

Conclusion: I, II, III, VI, VIII and IX were obtained from the plant for the first time, and I is a new compound.

MeSH terms

  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Molecular Conformation
  • Molecular Structure
  • Nigella / chemistry*
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification
  • Plants, Medicinal / chemistry*
  • Saponins / chemistry
  • Saponins / isolation & purification*
  • Seeds / chemistry
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification

Substances

  • Glycosides
  • Saponins
  • Sitosterols
  • beta-hederin
  • nigellamose
  • Oleanolic Acid
  • lyoniside