A case with epilepsy, cognitive impairment, renal microangiopathy and high titres of anticentromere and anticardiolipin antibodies

Lupus. 2005;14(8):625-8. doi: 10.1191/0961203305lu2125cr.

Abstract

We report a case with epileptic seizures, cognitive dysfunction, livedo reticularis, renal microangiopathy, acute myocardial infarction and high titres of anticentromere antibodies (ACA) and IgG/IgM anticardiolipin antibodies. This is a rare association between primary antiphospholipid syndrome and ACA positivity that has not been reported so far in the literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Anticardiolipin / blood*
  • Antiphospholipid Syndrome / blood
  • Antiphospholipid Syndrome / complications*
  • Centromere / immunology*
  • Cognition Disorders / blood
  • Cognition Disorders / etiology*
  • Epilepsy / blood
  • Epilepsy / etiology*
  • Humans
  • Male
  • Myocardial Infarction / blood
  • Myocardial Infarction / etiology
  • Renal Artery Obstruction / blood
  • Renal Artery Obstruction / etiology*
  • Skin Diseases, Vascular / blood
  • Skin Diseases, Vascular / etiology

Substances

  • Antibodies, Anticardiolipin