Duplex and hairpin dimer structures for perylene diimide-oligonucleotide conjugates

Chem Commun (Camb). 2005 Oct 14:(38):4795-7. doi: 10.1039/b509754a. Epub 2005 Sep 1.

Abstract

Perylene diimide-oligonucleotide conjugates can form either duplex or hairpin dimer structures, depending upon the choice of oligonucleotide base sequence; we have used a combination of optical spectroscopy and molecular modeling to investigate the structures of the duplex and hairpin dimer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Circular Dichroism
  • DNA / chemistry
  • Dimerization
  • Imides / chemistry*
  • Macromolecular Substances / chemical synthesis
  • Macromolecular Substances / chemistry
  • Models, Molecular
  • Molecular Structure
  • Oligonucleotides / chemistry*
  • Perylene / analogs & derivatives
  • Perylene / chemistry*

Substances

  • Imides
  • Macromolecular Substances
  • Oligonucleotides
  • Perylene
  • DNA