A multicenter point-prevalence study: antimicrobial prescription frequencies in hospitalized patients in Turkey

Ann Clin Microbiol Antimicrob. 2005 Oct 3:4:16. doi: 10.1186/1476-0711-4-16.

Abstract

Background: Accurate information about prescribing patterns in hospitals is valuable in improving the quality of antimicrobial prescriptions.

Methods: Data on the use of antimicrobial agents in eighteen tertiary care hospitals were collected on March 20th 2002.

Results: One or more antimicrobials were ordered in 2900 (30.6%)of 9471 hospitalized patients. The reasons of hospitalization of the patients receiving antimicrobials were medical treatment (42.5%), elective surgery (39.6%), treatment of infectious disease (17.1%) and emergent surgical procedures (10.4%). The highest consumption frequencies were found in surgical (81.6%) and medical (55.2%) intensive care units. The 48.8% of antimicrobials were given for treatment and 44.2% for prophylactic use. The most common reasons for treatment were found as lower respiratory tract, urinary tract, surgical wound infections and febrile neutropenia. Antimicrobials were ordered empirically in 78.4% of patients. The proven infection ratio was found as 30.7%. The 56.4% and 13.4% of orders were evaluated as clinically and microbiologically appropriate respectively.

Conclusion: These results suggest that antimicrobial prescription and empirical treatment ratios were high and inappropriate at inpatient groups.

Publication types

  • Multicenter Study

MeSH terms

  • Anti-Infective Agents / therapeutic use*
  • Antibiotic Prophylaxis
  • Drug Costs
  • Drug Therapy, Combination
  • Drug Utilization*
  • Hospitalization
  • Humans
  • Prospective Studies

Substances

  • Anti-Infective Agents