Patients with a body surface area less than 1.7 m2 have a good outcome with the CardioWest Total Artificial Heart

J Heart Lung Transplant. 2005 Oct;24(10):1501-5. doi: 10.1016/j.healun.2005.01.016.

Abstract

Background: A body surface area (BSA) of 1.7 m2 was considered as the lower limit to implant a CardioWest Total Artificial Heart (TAH). We reviewed our experience with the TAH in patients with a BSA of less than 1.7 m2.

Methods: From April 1986 to May 2003, among 149 patients implanted with a TAH in our institution, 30 had a BSA of less than 1.7 m2 (Group I). Results were compared with the remaining 119 patients (Group II).

Results: One patient in Group I experienced a fitting problem and was left with the chest open. Otherwise, in this group, the Day 1 cardiac index averaged 3.6 +/- 0.6 liter/min/m2, which was significantly higher than the 2.8 +/- 0.36 liter/min/m2 observed in Group II. Post-implantation central venous pressure and mean arterial pressure were similar in both groups: 14.7 +/- 3.8 mm Hg vs 14.5 +/- 4 mm Hg and 87 +/- 23 mm Hg vs 88 +/- 19 mm Hg, respectively. In Group I, survival on the device dramatically increased from 9% before 1992, to 36% between 1992 and 1997 and finally reached 75% after then. In the meantime, for the same time periods, global survival to hospital discharge increased from 9% to 36% and reached 50% after 1997. In Group II, global survival to hospital discharge was 25.5% before 1992, 34.6% between 1993 and 1997, and reached 52% thereafter.

Conclusion: The CardioWest TAH can be used in patients with a BSA between 1.5 m2 and 1.7 m2 with few fitting problems. In this group of patients, results are similar to those obtained in patients with a BSA greater than 1.8 m2.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Body Surface Area*
  • Child
  • Female
  • Heart Failure / surgery*
  • Heart, Artificial*
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications
  • Risk Factors
  • Survival Analysis
  • Treatment Outcome