Sleep-disordered breathing and cardiovascular health

Curr Opin Pulm Med. 2005 Nov;11(6):501-6. doi: 10.1097/01.mcp.0000183058.52924.70.

Abstract

Purpose of review: Sleep-disordered breathing is a widely prevalent condition and may have serious medical, social, and economic consequences. This review evaluates the role of sleep-disordered breathing in cardiovascular morbidity and mortality on the basis of recent literature.

Recent findings: Epidemiologic studies, retrospective reviews, and prospective clinical trials suggest a strong association between sleep-disordered breathing and adverse cardiovascular events. Individuals with sleep-disordered breathing have a higher prevalence of hypertension, which attenuates with treatment. Furthermore, the presence of sleep-disordered breathing augurs an increased risk of coronary artery disease, cardiac arrhythmias, and heart failure.

Summary: Recent research provides an emerging evidence of the role of sleep-disordered breathing as a risk factor for diverse cardiovascular disorders.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / etiology*
  • Endothelium, Vascular / physiopathology
  • Female
  • Glucose Metabolism Disorders / etiology*
  • Heart / physiopathology
  • Humans
  • Hypertension, Pulmonary / etiology*
  • Male
  • Respiration
  • Risk Factors
  • Sleep Apnea, Obstructive / complications*
  • Sleep Apnea, Obstructive / physiopathology