Therapeutic approaches to Chlamydia infections

Expert Opin Pharmacother. 2005 Oct;6(13):2281-90. doi: 10.1517/14656566.6.13.2281.

Abstract

Chlamydia trachomatis ocular and urogenital infections represent major public health problems, whereas Chlamydophila pneumoniae is a common aetiological agent of community-acquired pneumonia. The obligate intracellular lifestyle of these established pathogens poses challenges to both their diagnosis and treatment. Tetracyclines, macrolides and quinolones remain the antimicrobials of choice for the treatment of infections due to Chlamydiaceae.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use*
  • Chlamydia Infections / drug therapy*
  • Chlamydia Infections / microbiology
  • Chlamydia trachomatis / drug effects*
  • Chlamydia trachomatis / isolation & purification
  • Chlamydophila pneumoniae / drug effects*
  • Chlamydophila pneumoniae / isolation & purification
  • Conjunctivitis, Inclusion / drug therapy*
  • Conjunctivitis, Inclusion / microbiology
  • Female Urogenital Diseases / drug therapy*
  • Female Urogenital Diseases / microbiology
  • Humans
  • Macrolides / pharmacology
  • Macrolides / therapeutic use
  • Pneumonia, Bacterial / drug therapy*
  • Pneumonia, Bacterial / microbiology
  • Practice Guidelines as Topic
  • Quinolones / pharmacology
  • Quinolones / therapeutic use
  • Randomized Controlled Trials as Topic
  • Tetracyclines / pharmacology
  • Tetracyclines / therapeutic use
  • Trachoma / drug therapy*
  • Trachoma / microbiology

Substances

  • Anti-Bacterial Agents
  • Macrolides
  • Quinolones
  • Tetracyclines