Regioselective sonochemical synthesis of genistein derivatives

S F Wang; Y H Ye; Z Zhang; R X Tan

doi:10.1016/j.ultsonch.2004.10.002

Regioselective sonochemical synthesis of genistein derivatives

Ultrason Sonochem. 2006 Jan;13(1):28-31. doi: 10.1016/j.ultsonch.2004.10.002. Epub 2004 Dec 10.

Authors

S F Wang¹, Y H Ye, Z Zhang, R X Tan

Affiliation

¹ Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, 210093, People's Republic of China.

PMID: 16223683
DOI: 10.1016/j.ultsonch.2004.10.002

Abstract

Differential functionalization of the phenolic groups in genistein was carried out in excellent yields under ultrasonic irradiation. The isoflavone ring had proved to be unstable under stirring at 60 degrees C and phenyl benzyl ketone was unexpectedly isolated instead of the genistein derivative.

MeSH terms

Genistein / analogs & derivatives*
Genistein / chemical synthesis*
Genistein / isolation & purification
Genistein / radiation effects
Isomerism
Sonication*

Substances

Genistein