Abstract
Purpose:
To report a case of bilateral endogenous Phialemonium curvatum endophthalmitis, secondary to intrapenile injections for erectile dysfunction.
Design:
Observational case report.
Methods:
A 71-year-old man with P. curvatum endocarditis and bilateral decreased vision was diagnosed as having bilateral endogenous endophthalmitis. P. curvatum was identified in cultures that were performed on samples of the vitreous. Treatment consisted of bilateral vitrectomy and intraocular and systemic antifungals.
Results:
Despite resolution of the systemic infection, the patient's postoperative visual acuity remained limited to hand movement, and the ophthalmic clinical picture remained unchanged.
Conclusions:
P. curvatum is a pathogen that can be readily isolated from the vitreous. The authors are unaware of previous reported cases of ocular infection that was caused by P. curvatum.
MeSH terms
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Aged
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Antifungal Agents / therapeutic use
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Ascomycota / isolation & purification*
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Cataract Extraction
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Drug Contamination
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Endocarditis / drug therapy
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Endocarditis / microbiology
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Endophthalmitis / diagnostic imaging
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Endophthalmitis / drug therapy
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Endophthalmitis / microbiology*
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Erectile Dysfunction / drug therapy
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Eye Infections, Fungal* / diagnostic imaging
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Eye Infections, Fungal* / drug therapy
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Eye Infections, Fungal* / microbiology
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Fungemia / drug therapy
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Fungemia / microbiology
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Humans
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Male
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Muscle, Smooth / drug effects
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Mycoses* / diagnostic imaging
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Mycoses* / drug therapy
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Mycoses* / microbiology
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Parasympatholytics / administration & dosage
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Pyrimidines / therapeutic use
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Triazoles / therapeutic use
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Ultrasonography
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Vitrectomy
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Vitreous Body / diagnostic imaging
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Vitreous Body / microbiology
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Voriconazole
Substances
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Antifungal Agents
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Parasympatholytics
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Pyrimidines
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Triazoles
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Voriconazole