Abstract
Stable isotope labeled 3-acetyldeoxynivalenol (3-AcDON) was synthesized in excellent yield from deoxynivalenol as starting material. This is the first synthesis of a stable isotope labeled type-B trichothecene suitable as internal standard for HPLC-MS/MS or GC-MS analysis of trichothecene mycotoxins. The isotopic purity of the 3-d(3)-AcDON was determined to be 94.9%.
MeSH terms
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Chromatography, High Pressure Liquid / standards
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Gas Chromatography-Mass Spectrometry / standards
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Isotope Labeling / methods*
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Mass Spectrometry / standards
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Molecular Structure
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Mycotoxins / analysis
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Trichothecenes / analysis
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Trichothecenes / chemical synthesis*
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Trichothecenes / chemistry
Substances
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Mycotoxins
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Trichothecenes
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3-acetyldeoxynivalenol
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deoxynivalenol