An unusual case of thrombocytosis associated with concurrent cytomegalovirus and respiratory syncytial virus infection in an immunocompetent infant: possible roles of thrombopoietin and interleukin-6

Izumi Akaboshi; Kaoru Fugita; Akio Abe; Toshio Tanaka

doi:10.1016/j.jinf.2004.09.014

An unusual case of thrombocytosis associated with concurrent cytomegalovirus and respiratory syncytial virus infection in an immunocompetent infant: possible roles of thrombopoietin and interleukin-6

J Infect. 2005 Oct;51(3):e97-100. doi: 10.1016/j.jinf.2004.09.014. Epub 2004 Dec 13.

Authors

Izumi Akaboshi¹, Kaoru Fugita, Akio Abe, Toshio Tanaka

Affiliation

¹ Akaboshi Paediatric Clinic, 1-16-16, Kuwamizu-machi, Kumamoto, Japan. [email protected]

PMID: 16230213
DOI: 10.1016/j.jinf.2004.09.014

Abstract

This is the case study of concurrent cytomegalovirus and respiratory syncytial virus infection in an infant who showed thrombocytosis, liver dysfunction and bronchiolitis. The combination of thrombocytosis with this co-infection is causally related to elevated levels of thrombopoietin and interleukin-6. This study represents the first such case ever recorded.

Publication types

Case Reports

MeSH terms

Antibodies, Viral / blood
Cytomegalovirus / immunology
Cytomegalovirus Infections / complications*
Cytomegalovirus Infections / diagnosis
Humans
Immunocompetence
Infant
Interleukin-6 / blood*
Male
Respiratory Syncytial Virus Infections / complications*
Respiratory Syncytial Virus Infections / diagnosis
Respiratory Syncytial Virus, Human / immunology
Thrombocytosis / etiology*
Thrombopoietin / blood*

Substances

Antibodies, Viral
Interleukin-6
Thrombopoietin