The changing natural history of HIV disease: before and after the introduction of generic antiretroviral therapy in southern India

Clin Infect Dis. 2005 Nov 15;41(10):1525-8. doi: 10.1086/497267. Epub 2005 Oct 13.

Abstract

The number of individuals seeking treatment for infection with human immunodeficiency virus increased as the cost of highly active antiretroviral therapy (HAART) decreased 20-fold after the introduction of generic HAART in India in the year 2000. The incidence of tuberculosis and opportunistic infections decreased to <2 cases per 100 person-years. Death rates decreased from 25 to 5 deaths per 100 person-years between 1997 and 2003.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology
  • Anti-HIV Agents / adverse effects
  • Anti-HIV Agents / economics
  • Anti-HIV Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active / adverse effects
  • Antiretroviral Therapy, Highly Active / economics
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology*
  • Humans
  • India / epidemiology
  • Time Factors

Substances

  • Anti-HIV Agents