Radiofrequency ablation in a porcine lung model: correlation between CT and histopathologic findings

AJR Am J Roentgenol. 2005 Nov;185(5):1299-306. doi: 10.2214/AJR.04.0968.

Abstract

Objective: The objective of our study was to investigate the time course changes of the ablated lesion after radiofrequency ablation in the porcine lung and the correlation between CT and histopathologic findings.

Conclusion: Ground-glass attenuation on CT led to overestimation of the size of necrotic lesions. The layered structural findings on CT were consistent with the histopathologic findings. Although CT findings reflect the histopathologic findings, attention should be paid to the dissociation of ablated lesions and high-density areas in clinical interpretation of CT images.

MeSH terms

  • Animals
  • Catheter Ablation* / adverse effects
  • Image Processing, Computer-Assisted
  • Lung / diagnostic imaging*
  • Lung / surgery*
  • Lung Injury
  • Necrosis
  • Poisson Distribution
  • Radiography, Interventional
  • Swine
  • Time Factors
  • Tomography, X-Ray Computed*