Abstract
[reaction: see text] New artemisinin-derived dimers, fluorinated or not, have been prepared by a self-cross metathesis reaction in the presence of first- or second-generation ruthenium catalysts without degradation of the endoperoxide bridge and with a good E/Z selectivity (up to 100:0).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemical synthesis*
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Antineoplastic Agents, Phytogenic / chemistry
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Artemisinins / chemical synthesis*
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Artemisinins / chemistry
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Catalysis
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Cell Line, Tumor
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Drug Screening Assays, Antitumor
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Humans
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Molecular Structure
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Sesquiterpenes / chemical synthesis*
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Sesquiterpenes / chemistry
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Stereoisomerism
Substances
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Antineoplastic Agents, Phytogenic
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Artemisinins
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Sesquiterpenes
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artemisinin