Acute respiratory failure revealing adult-onset Still's disease: diagnostic value of low glycosylated ferritin level

Clin Rheumatol. 2006 Sep;25(5):766-8. doi: 10.1007/s10067-005-0078-0. Epub 2005 Nov 10.

Abstract

The authors report three cases of adult-onset Still's disease with severe hypoxemic pulmonary involvement, mimicking severe pulmonary sepsis. Clinicians must be aware of this rare form of such disease. Low (<20%) glycosylated ferritin level in the presence of unexplained prolonged fever with leukocytosis can help in the diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Diagnosis, Differential
  • Female
  • Ferritins / blood
  • Fever / complications
  • Fever / diagnosis
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Leukocytosis / complications
  • Leukocytosis / diagnosis
  • Male
  • Methylprednisolone / therapeutic use
  • Prednisolone / therapeutic use
  • Respiratory Insufficiency / complications
  • Respiratory Insufficiency / diagnosis*
  • Sepsis / complications
  • Sepsis / diagnosis*
  • Still's Disease, Adult-Onset / blood
  • Still's Disease, Adult-Onset / complications
  • Still's Disease, Adult-Onset / diagnosis*
  • Still's Disease, Adult-Onset / drug therapy
  • Treatment Outcome

Substances

  • Immunoglobulins, Intravenous
  • glycosylated ferritin
  • Ferritins
  • Prednisolone
  • Methylprednisolone