Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer

BJU Int. 2005 Dec;96(9):1241-6. doi: 10.1111/j.1464-410X.2005.05821.x.
No abstract available

Publication types

  • Review

MeSH terms

  • Androgen Antagonists / therapeutic use*
  • Androgen Receptor Antagonists*
  • Androstenes
  • Androstenols / therapeutic use*
  • Animals
  • Drug Evaluation
  • Humans
  • Lyases / antagonists & inhibitors*
  • Male
  • Mice
  • Neoplasm Metastasis / drug therapy
  • Prostatic Neoplasms / drug therapy*
  • Prostatic Neoplasms / pathology
  • Steroid 17-alpha-Hydroxylase / physiology

Substances

  • Androgen Antagonists
  • Androgen Receptor Antagonists
  • Androstenes
  • Androstenols
  • Steroid 17-alpha-Hydroxylase
  • Lyases
  • abiraterone