Abstract
Type 2 diabetes mellitus is a heterogeneous condition in which the clinical manifestation of hyperglycemia is a reflection of the impaired balance between insulin sensitivity and insulin secretion. Clinical experience and research in youth type 2 diabetes mellitus are in an early stage because of the relative novelty of the condition in pediatrics. This article discusses the amassed information in type 2 diabetes mellitus of youth to date with respect to the epidemiology, pathophysiology, risk factors, clinical presentation, screening, and management strategies.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Autoantibodies / blood
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Child
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Diabetes Complications / metabolism
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Diabetes Complications / therapy
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Diabetes Mellitus, Type 2 / diagnosis
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Diabetes Mellitus, Type 2 / immunology
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Diabetes Mellitus, Type 2 / therapy*
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Diet
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Dyslipidemias / drug therapy
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Dyslipidemias / etiology
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Humans
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Hyperglycemia / drug therapy
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Hyperglycemia / etiology
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Hypertension / drug therapy
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Hypertension / etiology
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Hypoglycemic Agents / therapeutic use
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Insulin Resistance
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Insulin-Secreting Cells / pathology
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Life Style
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Metformin / therapeutic use
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Risk Factors
Substances
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Autoantibodies
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Hypoglycemic Agents
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Metformin