Abstract
The authors investigated whether the amplitude and latency of diaphragm compound muscle action potential helped predict respiratory failure in Guillain-Barré syndrome. Both variables were significantly but weakly correlated with vital capacity (VC) and were similar in unventilated (n = 60) and ventilated (n = 10) patients. In ventilated patients, motor loss severity, progression, and VC reduction were significantly greater, and bulbar dysfunction was more common. Predicting respiratory failure must rely on clinical features and VC.
MeSH terms
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Action Potentials / physiology
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Adult
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Aged
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Diaphragm / innervation
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Diaphragm / physiopathology*
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Disease Progression
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Electrodiagnosis / methods
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Female
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Guillain-Barre Syndrome / complications*
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Guillain-Barre Syndrome / physiopathology*
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Humans
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Male
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Middle Aged
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Muscle Contraction / physiology
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Muscle Weakness / diagnosis
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Muscle Weakness / etiology
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Muscle Weakness / physiopathology
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Neural Conduction / physiology
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Phrenic Nerve / physiopathology*
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Predictive Value of Tests
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Reaction Time / physiology
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Respiratory Center / physiopathology
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Respiratory Insufficiency / diagnosis*
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Respiratory Insufficiency / etiology
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Respiratory Insufficiency / physiopathology*
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Vital Capacity / physiology