Abstract
The new isoprenylated diketopiperazine roquefortine E (6) has been isolated from an Australian soil isolate of the ascomycete Gymnoascus reessii. The known fungal metabolite roquefortine C (1) was also recovered as the major antibacterial principle, and all structures were assigned by detailed spectroscopic analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Ascomycota / chemistry*
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Australia
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Heterocyclic Compounds, 4 or More Rings / chemistry
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Heterocyclic Compounds, 4 or More Rings / isolation & purification*
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Heterocyclic Compounds, 4 or More Rings / pharmacology
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Indoles / chemistry
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Indoles / isolation & purification*
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Indoles / pharmacology
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Molecular Structure
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Mycotoxins / chemistry
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Mycotoxins / isolation & purification*
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Mycotoxins / pharmacology
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Nuclear Magnetic Resonance, Biomolecular
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Piperazines / chemistry
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Piperazines / isolation & purification*
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Piperazines / pharmacology
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Soil Microbiology
Substances
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Anti-Bacterial Agents
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Heterocyclic Compounds, 4 or More Rings
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Indoles
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Mycotoxins
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Piperazines
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roquefortine E
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roquefortine