Synthesis of the core structure of the fungal metabolite benesudon: use of oxidative decarboxylation

Derrick L J Clive; Minaruzzaman; Haikang Yang

doi:10.1021/ol052131g

Synthesis of the core structure of the fungal metabolite benesudon: use of oxidative decarboxylation

Org Lett. 2005 Dec 8;7(25):5581-3. doi: 10.1021/ol052131g.

Authors

Derrick L J Clive¹, Minaruzzaman, Haikang Yang

Affiliation

¹ Chemistry Department, University of Alberta, Edmonton, Alberta, Canada T6G 2G2. [email protected]

PMID: 16320996
DOI: 10.1021/ol052131g

Abstract

[chemical reaction: see text]. The core structure (5) of the fungal metabolite benesudon (1) was synthesized, the key step being oxidative decarboxylation of acid 17.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkylating Agents
Fungi / chemistry
Indicators and Reagents
Molecular Structure
Oxidation-Reduction
Pyrans / chemical synthesis
Pyrans / chemistry

Substances

Alkylating Agents
Indicators and Reagents
Pyrans
benesudon