Abstract
Anti-tumor necrosis factor-a (anti-TNF-a) therapy strategies result in significant clinical benefits in patients with rheumatoid arthritis, but with an increased rate of serious infectious diseases. We describe a patient receiving infliximab who developed a primary cutaneous Nocardia otitidiscaviarum infection after a skin injury.
MeSH terms
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Aged
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Antibodies, Monoclonal / adverse effects*
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Antibodies, Monoclonal / therapeutic use
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Antirheumatic Agents / adverse effects*
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Antirheumatic Agents / therapeutic use
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Arthritis, Rheumatoid / complications
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Arthritis, Rheumatoid / drug therapy*
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Diabetes Mellitus, Type 1 / complications
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Humans
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Infliximab
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Male
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Nocardia Infections / chemically induced*
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Nocardia Infections / pathology
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Skin / injuries
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Skin Diseases, Bacterial / chemically induced*
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Skin Diseases, Bacterial / pathology
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Tumor Necrosis Factor-alpha / antagonists & inhibitors
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Wounds and Injuries / microbiology
Substances
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Antibodies, Monoclonal
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Antirheumatic Agents
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Tumor Necrosis Factor-alpha
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Infliximab