Esophageal squamous cell carcinoma after liver transplantation

Clin Transl Oncol. 2005 Dec;7(11):518-20. doi: 10.1007/BF02717007.

Abstract

The occurrence of an oesophageal squamous cell carcinoma following liver transplantation is very infrequent. Such an event has been related to a history of alcohol-induced cirrhosis, as in other squamous cell tumours of the oropharynx. We report the case of a 64-year-old male patient diagnosed as having oesophageal squamous cell carcinoma six years after having had a liver transplant due to alcohol-induced cirrhosis. The tumour was treated surgically and consisted of an Ivor-Lewis oesophagectomy. The patient is disease-free 17 months after surgery. A review of the cases reported in the literature indicated treatment with chemotherapy and radiation therapy, and with excision in some cases. Generally, despite aggressive treatment the prognosis is poor.

Publication types

  • Case Reports

MeSH terms

  • Alcoholism / complications*
  • Carcinoma, Squamous Cell / etiology*
  • Carcinoma, Squamous Cell / surgery
  • Cardia / pathology*
  • Cardia / surgery
  • Deglutition Disorders / etiology
  • Esophageal Neoplasms / etiology*
  • Esophageal Neoplasms / surgery
  • Esophageal Stenosis / etiology
  • Esophagectomy
  • Humans
  • Immunocompromised Host
  • Immunosuppression Therapy / adverse effects*
  • Immunosuppressive Agents / adverse effects*
  • Liver Cirrhosis, Alcoholic / surgery
  • Liver Transplantation*
  • Male
  • Middle Aged
  • Neoplasms, Multiple Primary / etiology*
  • Neoplasms, Multiple Primary / surgery
  • Postoperative Complications / etiology*
  • Remission Induction
  • Stomach Neoplasms / etiology*
  • Stomach Neoplasms / surgery
  • Tacrolimus / adverse effects*

Substances

  • Immunosuppressive Agents
  • Tacrolimus