NMR characterization of kinase p38 dynamics in free and ligand-bound forms

Angew Chem Int Ed Engl. 2006 Jan 30;45(6):993-7. doi: 10.1002/anie.200502770.
No abstract available

MeSH terms

  • Animals
  • Crystallography, X-Ray
  • Dimethyl Sulfoxide
  • Drug Design
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Mice
  • Models, Molecular
  • Phenylalanine / chemistry
  • Plasmids
  • p38 Mitogen-Activated Protein Kinases / antagonists & inhibitors
  • p38 Mitogen-Activated Protein Kinases / chemistry*
  • p38 Mitogen-Activated Protein Kinases / metabolism*

Substances

  • Enzyme Inhibitors
  • Ligands
  • Phenylalanine
  • p38 Mitogen-Activated Protein Kinases
  • Dimethyl Sulfoxide