The high-energy programme of the HINDAS European project has provided a large amount of experimental data and led to a better understanding of the spallation reaction mechanism and the development of more reliable spallation models. These data, or the new models, which have been implemented into high-energy transport codes, can be now used to predict with a larger confidence or, at least with a known uncertainty, some important quantities for the design of spallation sources. In this paper, examples concerning the residue production in a Pb-Bi target and the high-energy neutrons escaping the target are presented. In the first case, the activity and the amount of radioactive volatile elements that can be released, in case of a containment failure, are calculated and the level of confidence of the calculation is assessed. The second example shows that the models correctly predict the high-energy tail of the neutron spectrum, which is important for radioprotection in the facility.