Gabapentin in the treatment of severe sweating experienced by advanced cancer patients

Giampiero Porzio; Federica Aielli; Lucilla Verna; Claudio Porto; Paolo Aloisi; Katia Cannita; Enrico Ricevuto; Paolo Marchetti; Corrado Ficorella

doi:10.1007/s00520-005-0014-5

Gabapentin in the treatment of severe sweating experienced by advanced cancer patients

Support Care Cancer. 2006 Apr;14(4):389-91. doi: 10.1007/s00520-005-0014-5. Epub 2006 Jan 10.

Authors

Giampiero Porzio¹, Federica Aielli, Lucilla Verna, Claudio Porto, Paolo Aloisi, Katia Cannita, Enrico Ricevuto, Paolo Marchetti, Corrado Ficorella

Affiliation

¹ Supportive Care Task Force, Medical Oncology Department, University of L'Aquila, L'Aquila, Italy. [email protected]

PMID: 16402235
DOI: 10.1007/s00520-005-0014-5

Abstract

Nine patients with advanced cancer suffering from idiopathic severe sweating were treated with gabapentin (600-1,800 mg/day). All patients responded to the treatment; five patients experienced transient drowsiness. Gabapentin seems to be a safe and effective treatment for idiopathic sweating in advanced cancer patients. Further studies are warranted to confirm or refute these results.

Publication types

Case Reports

MeSH terms

Adult
Aged
Amines / administration & dosage
Amines / therapeutic use*
Anti-Anxiety Agents / administration & dosage
Anti-Anxiety Agents / therapeutic use*
Cyclohexanecarboxylic Acids / administration & dosage
Cyclohexanecarboxylic Acids / therapeutic use*
Female
Gabapentin
Humans
Italy
Male
Middle Aged
Neoplasms / physiopathology*
Sweating / drug effects*
gamma-Aminobutyric Acid / administration & dosage
gamma-Aminobutyric Acid / therapeutic use*

Substances

Amines
Anti-Anxiety Agents
Cyclohexanecarboxylic Acids
gamma-Aminobutyric Acid
Gabapentin