[Sensitivity of influenza A/H5 viruses isolated from wild birds on the territory of Russia to arbidol in the cultured MDCK cells]

I T Fediakina; I A Leneva; S S Iamnikova; D K Livov; R G Glushkov; A M Shuster

[Sensitivity of influenza A/H5 viruses isolated from wild birds on the territory of Russia to arbidol in the cultured MDCK cells]

Vopr Virusol. 2005 Nov-Dec;50(6):32-5.

[Article in Russian]

Authors

I T Fediakina, I A Leneva, S S Iamnikova, D K Livov, R G Glushkov, A M Shuster

PMID: 16408629

Abstract

The effect of the antiviral drug arbidol on the reproduction of avian influenza A/H5 viruses was studied in in vitro experiments. The strains were isolated from the wild birds of Eastern Siberia and they were closely related to the 1997-2000 viruses from South-Eastern Asia. Arbidol was shown to exert a selective inhibiting effect on the reproduction of these viruses in the MDCH cell cultures.

MeSH terms

Animals
Animals, Wild / virology
Antiviral Agents / pharmacology*
Birds / virology
Cell Line
Dogs
Dose-Response Relationship, Drug
Indoles / pharmacology*
Influenza A Virus, H5N2 Subtype / drug effects*
Influenza A Virus, H5N2 Subtype / physiology
Influenza in Birds / virology
Microbial Sensitivity Tests
Virus Replication / drug effects

Substances

Antiviral Agents
Indoles
umifenovir