[The renal pathology in light chain deposition disease]

G Ital Nefrol. 2005 Nov-Dec:22 Suppl 33:S53-6.
[Article in Italian]

Abstract

Light Chain Deposition Disease (LCDD) is a relatively frequent renal disease associated with dysproteinemia. Although the light chain deposits can be widespread, the kidney is the most frequently involved organ, and renal involvement can dominate the clinical condition. The morphological features of LCDD can be recognized by light microscopy; however, the diagnosis can be made certain only by immunofluorescence microscopy, using antisera to kappa and lambda chains, and by electron microscopy.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Humans
  • Immunoglobulin Light Chains*
  • Kidney Diseases / etiology*
  • Kidney Diseases / pathology
  • Paraproteinemias / complications*

Substances

  • Immunoglobulin Light Chains