Atypical manifestations of multiple myeloma: radiological appearance

Eur J Radiol. 2006 May;58(2):280-5. doi: 10.1016/j.ejrad.2005.11.015. Epub 2006 Jan 23.

Abstract

Diagnostic procedures performed on patients with multiple myeloma typically reveal lytic bone lesions, osteopenia or osteoporosis, bone marrow infiltration by plasma cells as well as overproduction of immunoglobulin or light chains in the serum or urine. Skeletal manifestations are extremely variable and the unusual forms have been described extensively. Extramedullary plasma-cell tumours (plasmocytoma) are found in about 5% of newly diagnosed patients with multiple myelomas. In this paper we present eight patients with atypical forms of multiple myeloma.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / diagnosis*
  • Abdominal Neoplasms / drug therapy
  • Abdominal Neoplasms / radiotherapy
  • Aged
  • Amyloidosis / complications
  • Amyloidosis / diagnosis
  • Amyloidosis / drug therapy
  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Humans
  • Liver / pathology
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / secondary
  • Lung / diagnostic imaging
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / radiotherapy
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Multiple Myeloma / diagnosis*
  • Multiple Myeloma / drug therapy
  • Multiple Myeloma / radiotherapy
  • Nasopharyngeal Neoplasms / diagnosis*
  • Nasopharyngeal Neoplasms / drug therapy
  • Peritoneal Cavity / diagnostic imaging
  • Peritoneal Neoplasms / diagnosis*
  • Peritoneal Neoplasms / drug therapy
  • Radiography, Abdominal / methods
  • Sphenoid Sinus / pathology
  • Spinal Neoplasms / diagnosis*
  • Spinal Neoplasms / pathology
  • Spinal Neoplasms / radiotherapy
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome