[Initial results of the Project of the German Breast Cancer Study Group on "Breast saving therapy of the small breast cancer"]

Chirurg. 1992 Jun;63(6):495-500.
[Article in German]

Abstract

In the German Breast Cancer Study Group (GBSG) multicenter trial "Breast preservation in small breast cancer" 1119 patients were accrued over a period of six years. The study was originally designed as a randomized trial which had to be changed into a prospective observation study. A high therapeutic standard was guaranteed by quality control. The univariate analysis of prognostic variables was the first step to a valid treatment comparison. Those factors determined as being significant were combined with the treatment effects in a multivariate analysis. The published results were obtained after a median observation time of four years.

Publication types

  • Clinical Trial
  • English Abstract
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms / mortality
  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Lymphatic Metastasis
  • Mastectomy, Segmental / methods*
  • Middle Aged
  • Neoplasm Staging
  • Neoplasms, Hormone-Dependent / mortality
  • Neoplasms, Hormone-Dependent / pathology
  • Neoplasms, Hormone-Dependent / surgery
  • Prospective Studies
  • Radiotherapy Dosage
  • Receptors, Estrogen / analysis
  • Receptors, Progesterone / analysis
  • Survival Rate

Substances

  • Receptors, Estrogen
  • Receptors, Progesterone