Abstract
Diagnosis of polyarteritis nodosa is often delayed due to the vast heterogeneity of initial clinical symptoms. The case presented shows the clinical image of the disease, leading from the first symptoms up to verification of the diagnosis by sural-nerve biopsy. We discuss the classification of the disease among other types of vasculitis, the classification criteria proposed by the American College of Rheumatology (ACR) as well as current therapeutic options. This case underlines the interdisciplinary character of the disease, challenging neurologists, dermatologists, rheumatologists and orthopedics alike.
MeSH terms
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Amines / administration & dosage
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Biopsy
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Cyclohexanecarboxylic Acids / administration & dosage
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Cyclophosphamide / administration & dosage
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Diagnosis, Differential
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Drug Administration Schedule
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Drug Therapy, Combination
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Female
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Gabapentin
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Humans
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Lymphocytes / pathology
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Methylprednisolone / administration & dosage
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Middle Aged
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Polyarteritis Nodosa / diagnosis*
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Polyarteritis Nodosa / drug therapy
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Polyarteritis Nodosa / pathology
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Referral and Consultation
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Sural Nerve / pathology
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gamma-Aminobutyric Acid / administration & dosage
Substances
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Amines
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Cyclohexanecarboxylic Acids
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gamma-Aminobutyric Acid
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Gabapentin
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Cyclophosphamide
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Methylprednisolone