Abstract
A multicenter study of NS5b hepatitis C virus (HCV) genotype determination involving 12 laboratories demonstrates that any laboratory with expertise in sequencing techniques would be able to provide a reliable HCV genotype for clinical and epidemiological purposes as long as they are provided a consensus reference sequence database.
Publication types
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Multicenter Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Consensus Sequence
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Databases, Genetic*
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Genotype
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Hepacivirus / classification*
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Hepacivirus / genetics
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Hepatitis C / epidemiology*
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Hepatitis C / virology
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Humans
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Laboratories / standards*
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Polymerase Chain Reaction
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Reference Standards
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Sequence Analysis, DNA
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Viral Nonstructural Proteins / genetics*
Substances
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Viral Nonstructural Proteins
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NS-5 protein, hepatitis C virus