Hypoxia and HIF-1alpha protect A549 cells from drug-induced apoptosis

Cell Death Differ. 2006 Sep;13(9):1611-3. doi: 10.1038/sj.cdd.4401864. Epub 2006 Feb 3.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis*
  • Cell Hypoxia
  • Cell Line, Tumor
  • Cobalt / pharmacology
  • Cyclooxygenase 2 / metabolism
  • Drug Resistance, Neoplasm*
  • Humans
  • Hypoxia-Inducible Factor 1, alpha Subunit / genetics
  • Hypoxia-Inducible Factor 1, alpha Subunit / metabolism*
  • Membrane Proteins / antagonists & inhibitors
  • Membrane Proteins / metabolism
  • Nitrobenzenes / pharmacology
  • RNA, Small Interfering / genetics
  • Staurosporine / pharmacology*
  • Sulfonamides / pharmacology

Substances

  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Membrane Proteins
  • Nitrobenzenes
  • RNA, Small Interfering
  • Sulfonamides
  • N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
  • Cobalt
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • cobaltous chloride
  • Staurosporine