Isolation and absolute configuration determination of aliphatic sulfates as the Daphnia kairomones inducing morphological defense of a phytoplankton

Chem Pharm Bull (Tokyo). 2006 Feb;54(2):271-4. doi: 10.1248/cpb.54.271.

Abstract

2,6-Dimethylheptyl sulfate (1) and 6-methyloctyl sulfate (3) were isolated from Daphnia pulex as the Daphnia kairomones that induced morphological defense of a freshwater phytoplankton Scenedesmus gutwinskii var. heterospina (NIES-802). The absolute stereochemistry at C2 of 1 was determined by (1)H-NMR analysis of the (R)-MTPA ester of alcohol 2. The absolute configuration at C6 of 3 was determined by Ohrui's method applied to alcohol 4.

MeSH terms

  • Alkanesulfonic Acids / chemistry*
  • Alkanesulfonic Acids / isolation & purification
  • Alkanesulfonic Acids / pharmacology*
  • Animals
  • Daphnia / chemistry*
  • Heptanes / chemistry*
  • Heptanes / isolation & purification
  • Heptanes / pharmacology*
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Scenedesmus / drug effects*
  • Scenedesmus / ultrastructure
  • Spectrometry, Mass, Fast Atom Bombardment
  • Stereoisomerism
  • Sulfates / chemistry*
  • Sulfates / isolation & purification
  • Sulfates / pharmacology*
  • Sulfuric Acid Esters / chemistry*
  • Sulfuric Acid Esters / isolation & purification
  • Sulfuric Acid Esters / pharmacology*

Substances

  • 2,6-dimethylheptyl sulfate
  • 6-methyloctyl sulfate
  • Alkanesulfonic Acids
  • Heptanes
  • Indicators and Reagents
  • Sulfates
  • Sulfuric Acid Esters