Observer efficiency in discrimination tasks simulating malignant and benign breast lesions imaged with ultrasound

IEEE Trans Med Imaging. 2006 Feb;25(2):198-209. doi: 10.1109/TMI.2005.862205.

Abstract

We investigate and extend the ideal observer methodology developed by Smith and Wagner to detection and discrimination tasks related to breast sonography. We provide a numerical approach for evaluating the ideal observer acting on radio frequency (RF) frame data, which involves inversion of large nonstationary covariance matrices, and we describe a power-series approach to computing this inverse. Considering a truncated power series suggests that the RF data be Wiener-filtered before forming the final envelope image. We have compared human performance for Wiener-filtered and conventional B-mode envelope images using psychophysical studies for 5 tasks related to breast cancer classification. We find significant improvements in visual detection and discrimination efficiency in four of these five tasks. We also use the Smith-Wagner approach to distinguish between human and processing inefficiencies, and find that generally the principle limitation comes from the information lost in computing the final envelope image.

Publication types

  • Clinical Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms*
  • Artificial Intelligence
  • Breast Neoplasms / diagnostic imaging*
  • Discrimination Learning
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Information Storage and Retrieval / methods
  • Observer Variation
  • Pattern Recognition, Automated / methods*
  • Pattern Recognition, Visual / physiology*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Task Performance and Analysis
  • Ultrasonography, Mammary / methods*