Abstract
The recent cloning of MIF receptor fills an important gap in our understanding of the molecular biology and immunology of MIF. The MIF receptor, like MIF, does not fall into any established family of protein mediators, providing both new challenges and opportunities for the structural and functional analysis of MIF signal transduction.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Animals
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Antigens, Differentiation, B-Lymphocyte / chemistry
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Antigens, Differentiation, B-Lymphocyte / genetics
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Antigens, Differentiation, B-Lymphocyte / metabolism*
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Cloning, Molecular
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Histocompatibility Antigens Class II / chemistry
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Histocompatibility Antigens Class II / genetics
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Histocompatibility Antigens Class II / metabolism*
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Humans
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Macrophage Migration-Inhibitory Factors / chemistry
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Macrophage Migration-Inhibitory Factors / metabolism*
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Models, Molecular
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Protein Structure, Quaternary*
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Receptors, Immunologic / chemistry
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Receptors, Immunologic / genetics
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Receptors, Immunologic / metabolism*
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Signal Transduction / physiology
Substances
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Antigens, Differentiation, B-Lymphocyte
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Histocompatibility Antigens Class II
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Macrophage Migration-Inhibitory Factors
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Receptors, Immunologic
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invariant chain
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macrophage migration inhibitory factor receptor