Chewing the fat: beta-oxidation in signalling and development

Trends Plant Sci. 2006 Mar;11(3):124-32. doi: 10.1016/j.tplants.2006.01.005. Epub 2006 Feb 21.

Abstract

Peroxisomal beta-oxidation is involved not only in fatty acid catabolism and lipid housekeeping but also in metabolism of hormones and amino acids in plants. Recent research in model species has led to new insights into the roles of this pathway in signalling and development, in particular regarding the involvement of beta-oxidation in jasmonic acid biosynthesis. Analysis of associated processes, such as the glyoxylate cycle and redox metabolism has also highlighted the importance of integration of beta-oxidation with cytosolic and mitochondrial metabolism. Mutations that disrupt beta-oxidation can have extremely pleiotropic effects, indicating important and varied roles for this pathway throughout the plant life cycle and making this an exciting topic for future research.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Mitochondria / metabolism
  • Mitochondrial Trifunctional Protein
  • Multienzyme Complexes / physiology*
  • Oxidation-Reduction
  • Peroxisomes / genetics
  • Peroxisomes / metabolism*
  • Plants / metabolism*
  • Signal Transduction*

Substances

  • Multienzyme Complexes
  • Mitochondrial Trifunctional Protein