Abstract
A 39-year-old man was hospitalized after divalproate self-poisoning. He presented coma requiring tracheal intubation and mechanical ventilation at 11 hours and central diabetes insipidus. Serum valproic acid concentration was 590 mg/l at 30 hours. Progressive improvement occurred after hydratation and administration of vasopressin.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Bipolar Disorder / complications
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Bipolar Disorder / drug therapy
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Coma / chemically induced
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Diabetes Insipidus / chemically induced*
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Diabetes Insipidus / drug therapy
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Diabetes Insipidus / therapy
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Fluid Therapy
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Humans
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Intubation, Intratracheal
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Male
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Poisoning / blood
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Poisoning / therapy
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Polyuria / etiology
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Respiration, Artificial
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Suicide, Attempted
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Valproic Acid / poisoning*
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Vasopressins / therapeutic use
Substances
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Vasopressins
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Valproic Acid