Evaluation of CACNA1H in European patients with childhood absence epilepsy

Epilepsy Res. 2006 May;69(2):177-81. doi: 10.1016/j.eplepsyres.2006.01.009. Epub 2006 Feb 28.

Abstract

CACNA1H was evaluated in a resource of Caucasian European patients with childhood absence epilepsy by linkage analysis and typing of sequence variants previously identified in Chinese patients. Linkage analysis of 44 pedigrees provided no evidence for a locus in the CACNA1H region and none of the Chinese variants were found in 220 unrelated patients.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asian People / genetics*
  • Calcium Channels, T-Type / genetics*
  • Chromosome Mapping
  • DNA / genetics
  • Epilepsy, Absence / genetics*
  • Genetic Linkage*
  • Genotype
  • Humans
  • Microsatellite Repeats
  • Pedigree
  • White People / genetics*

Substances

  • CACNA1H protein, human
  • Calcium Channels, T-Type
  • DNA