Highly enantioselective hydrovinylation of alpha-alkyl vinylarenes. an approach to the construction of all-carbon quaternary stereocenters

J Am Chem Soc. 2006 Mar 8;128(9):2780-1. doi: 10.1021/ja057654y.

Abstract

The highly enantioselective hydrovinylation of alpha-alkyl vinylarenes was realized by using nickel complexes of chiral spiro phosphoramidite ligands. The method provided a new approach to the construction of chiral all-carbon quaternary centers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hydrocarbons, Aromatic / chemical synthesis*
  • Hydrocarbons, Aromatic / chemistry
  • Organophosphorus Compounds / chemistry
  • Stereoisomerism
  • Vinyl Compounds / chemical synthesis*
  • Vinyl Compounds / chemistry

Substances

  • Hydrocarbons, Aromatic
  • Organophosphorus Compounds
  • Vinyl Compounds
  • phosphoramidite