How senescent vascular cells lose their Clock age-dependent impairment of circadian rhythmicity in smooth muscle cells

Circ Res. 2006 Mar 3;98(4):450-2. doi: 10.1161/01.RES.0000214331.90904.aa.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • ARNTL Transcription Factors
  • Animals
  • Basic Helix-Loop-Helix Transcription Factors / genetics
  • CLOCK Proteins
  • Cell Cycle Proteins
  • Cellular Senescence*
  • Circadian Rhythm*
  • Cyclic AMP Response Element-Binding Protein / physiology
  • Gene Expression Regulation
  • Humans
  • Muscle, Smooth, Vascular / cytology
  • Muscle, Smooth, Vascular / metabolism*
  • Myocytes, Smooth Muscle / cytology
  • Myocytes, Smooth Muscle / metabolism*
  • Nitric Oxide / physiology
  • Nuclear Proteins / genetics
  • Period Circadian Proteins
  • Trans-Activators / genetics*

Substances

  • ARNTL Transcription Factors
  • BMAL1 protein, human
  • Basic Helix-Loop-Helix Transcription Factors
  • Cell Cycle Proteins
  • Cyclic AMP Response Element-Binding Protein
  • Nuclear Proteins
  • PER1 protein, human
  • Period Circadian Proteins
  • Trans-Activators
  • Nitric Oxide
  • CLOCK Proteins
  • CLOCK protein, human