Abstract
A sudden increase in neutropenic hematology patients with Candida krusei colonization and bacteremia prompted a longitudinal epidemiological investigation. We identified 39 patients; 13 developed candidemia, and three died; 25 patients carried the same genotype. We intervened by changing antifungal prophylaxis and implementing strict infection control measures. The incidence dropped immediately.
MeSH terms
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Antifungal Agents / administration & dosage
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Candida / genetics
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Candida / isolation & purification
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Candidiasis / epidemiology
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Candidiasis / microbiology
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Candidiasis / prevention & control
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Candidiasis / transmission*
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Fungemia / epidemiology
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Fungemia / microbiology
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Fungemia / prevention & control
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Genotype
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Hematologic Diseases / complications
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Humans
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Longitudinal Studies
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Netherlands / epidemiology
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Neutropenia / complications