Clinical value of image-guided fine needle aspiration of retroperitoneal masses and lymph nodes in gynecologic oncology

Gynecol Oncol. 2006 Oct;103(1):75-80. doi: 10.1016/j.ygyno.2006.01.039. Epub 2006 Mar 10.

Abstract

Objective: Evaluation of the sensitivity and specificity of fine needle aspiration of retroperitoneal masses and lymph nodes in gynecologic oncology.

Methods: Retrospective study of 101 punctures administered to 84 patients aged 23-86 years. The method's sensitivity and specificity were evaluated by clinical follow-up.

Results: A satisfactory sampling was obtained in 89.1% of punctures, and a cytological diagnosis was made in 88.1%. The size of the lymph nodes punctured was less than 14 mm in 46.5%. This test has a sensitivity of 87.5%, specificity of 88.9%, positive predictive value of 98%, negative predictive value of 53.3%, and accuracy of 87.7%. Four patients presented complications: pain (2), hematoma (1), and right ureteral perforation (1).

Conclusions: The fine needle aspiration technique has excellent positive predictive value and low morbidity. As a method of visualization, CT-scan, in combination with lymphography, allows the location of small lesions and the definition of their internal structures. The weak negative predictive value of fine needle aspiration might be correctible by laparoscopy-directed biopsy, and its potential is clearly ensured by the development of techniques for locating sentinel lymph nodes.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Fine-Needle / methods*
  • Biopsy, Fine-Needle / standards
  • Female
  • Genital Neoplasms, Female / pathology*
  • Humans
  • Lymph Nodes / pathology*
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology
  • Reproducibility of Results
  • Retroperitoneal Neoplasms / pathology*
  • Retrospective Studies
  • Sensitivity and Specificity