Does thrombolysis benefit patients with lacunar syndrome?

Eur Neurol. 2006;55(2):70-3. doi: 10.1159/000091982. Epub 2006 Mar 10.

Abstract

The efficacy of thrombolysis in clinical stroke subtypes is unclear. We compared the benefit of intravenous rt-PA in 11 patients with lacunar syndrome with that in 33 patients with a non-lacunar syndrome. Patients were matched by NIHSS score and time to treatment. Although no statistically significant differences were detected in outcome, the benefit was greater in the non- lacunar syndrome group.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Infarction / diagnosis
  • Brain Infarction / drug therapy*
  • Diagnostic Imaging
  • Female
  • Humans
  • Male
  • Middle Aged
  • Recombinant Proteins / therapeutic use
  • Retrospective Studies
  • Syndrome
  • Thrombolytic Therapy*
  • Tissue Plasminogen Activator / therapeutic use*
  • Treatment Outcome

Substances

  • Recombinant Proteins
  • Tissue Plasminogen Activator